Revenue - Reimbursement of R and D Costs (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Research and Development Reimbursement
Total reduction to R and D expense	$ 7,891	$ 10,078	$ 5,589
Janssen
Research and Development Reimbursement
Total reduction to R and D expense	5,819	8,554	5,129
Viatris
Research and Development Reimbursement
Total reduction to R and D expense	$ 2,072	$ 1,524	$ 460