Revenue (Tables)

12 Months Ended

Dec. 31, 2021

Revenue

Schedule of revenue recognized from collaborative arrangements

	Year Ended December 31,
(In thousands)	2021		2020		2019
Janssen	$	11,425	$	26,426	$	31,096
Other		38		38		154
Total collaboration revenue	$	11,463	$	26,464	$	31,250

Summary of changes in deferred revenue

	Year Ended December 31,
(In thousands)	2021		2020		2019
Collaboration revenue recognized in the period from:
Amounts included in deferred revenue at the beginning of the period	$	11,463	$	26,464	$	31,245
Performance obligations satisfied in previous period		—		—		—

Summary of profit sharing revenue and collaboration loss

	Year Ended December 31,
(In thousands)	2021		2020		2019
Viatris collaboration agreement - Amounts receivable from Viatris	$	43,848	$	43,893	$	13,664
Collaboration loss - Amounts payable to Viatris	$	—	$	—	$	1,582

Summary of the reductions to R&D costs related to reimbursement payments

	Year Ended December 31,
(In thousands)	2021		2020		2019
Janssen	$	5,819	$	8,554	$	5,129
Viatris		2,072		1,524		460
Total reduction to R&D expense, net	$	7,891	$	10,078	$	5,589