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Organization and Summary of Significant Accounting Policies - Related Parties (Details) - USD ($) $ in Thousands		12 Months Ended
	Feb. 14, 2020	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Related party transactions
Number of shares issued	5,500,000
Proceeds from the sale of ordinary shares, net		$ 139,915
GSK
Related party transactions
Ordinary shares held (in percent)		15.00%
Member board of directors
Related party transactions
Fees incurred related to related party		$ 500	$ 400	$ 500
NDA Group
Related party transactions
Ordinary shares held (in percent)		0.85%