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Revenue - Janssen Biotech Agreement (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
Feb. 28, 2018
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
Collaborative Arrangements and Co-Promote Agreement          
Percentage of profit share 33.00%     35.00%  
Revenue from collaborative arrangements   $ 5,488 $ 7,493 $ 12,120 $ 12,825
Research and development   62,404 46,399 128,417 100,217
Janssen          
Collaborative Arrangements and Co-Promote Agreement          
Upfront payment receivable $ 100,000        
Percentage of profit share 67.00%        
Maximum potential payments receivable $ 900,000        
Revenue from collaborative arrangements   5,479 7,392 12,101 12,715
Deferred revenue   25,700   25,700  
Research and development   $ 9,000 $ 9,000 $ 19,200 $ 17,700
Janssen | Collaborative Arrangement          
Collaborative Arrangements and Co-Promote Agreement          
Collaborative arrangement, future development and commercialization milestones 700,000        
Janssen | Collaborative Arrangement | TD-1473          
Collaborative Arrangements and Co-Promote Agreement          
Collaborative arrangement, opt in fee $ 200,000