Investments and Fair Value Measurements - Available-for-sale securities (Details) - USD ($) $ in Thousands	Dec. 31, 2019	Dec. 31, 2018
Available for sale securities:
Amortized Cost	$ 274,014	$ 501,837
Gross Unrealized Gains	148	8
Gross Unrealized Losses	(3)	(174)
Estimated Fair Value	274,159	501,671
Marketable securities
Available for sale securities:
Amortized Cost	238,278	207,086
Gross Unrealized Gains	148	8
Gross Unrealized Losses	(3)	(174)
Estimated Fair Value	238,423	206,920
US government securities \| Level 1
Available for sale securities:
Amortized Cost	100,746	48,807
Gross Unrealized Gains	108
Gross Unrealized Losses		(86)
Estimated Fair Value	100,854	48,721
US government agency securities \| Level 2
Available for sale securities:
Amortized Cost		9,852
Gross Unrealized Gains		2
Estimated Fair Value		9,854
Corporate notes \| Level 2
Available for sale securities:
Amortized Cost	25,466	57,508
Gross Unrealized Gains	9	6
Gross Unrealized Losses	(1)	(88)
Estimated Fair Value	25,474	57,426
Commercial paper \| Level 2
Available for sale securities:
Amortized Cost	112,066	90,919
Gross Unrealized Gains	31
Gross Unrealized Losses	(2)
Estimated Fair Value	112,095	90,919
Money market funds \| Level 1
Available for sale securities:
Amortized Cost	35,736	294,751
Estimated Fair Value	$ 35,736	$ 294,751

Amount, before tax, of unrealized gain in accumulated other comprehensive income (AOCI) on investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).

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