Number of performance milestones for recognition of Expenses associated with share based compensation arrangements.

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- Definition

Number of tranches for recognition of Expenses associated with share based compensation arrangements.

+ References

No definition available.

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- Definition

Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 1
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-URI http://asc.fasb.org/extlink&oid=116856206&loc=d3e5047-113901

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-Publisher FASB
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-Section S99
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-URI http://asc.fasb.org/extlink&oid=116856206&loc=d3e5070-113901

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- Definition

Amount of cost to be recognized for nonvested award under share-based payment arrangement. Excludes share and unit options.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
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-Paragraph 2
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-URI http://asc.fasb.org/extlink&oid=116856206&loc=d3e5070-113901

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- Definition

Period over which grantee's right to exercise award under share-based payment arrangement is no longer contingent on satisfaction of service or performance condition, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. Includes, but is not limited to, combination of market, performance or service condition.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
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- Definition

The number of non-vested equity-based payment instruments, excluding stock (or unit) options, that validly exist and are outstanding as of the balance sheet date.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
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-Section 50
-Paragraph 2
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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

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- Definition

Number of shares authorized for issuance under share-based payment arrangement.

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-Name Accounting Standards Codification
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Share-Based Compensation - Performance Contingent Awards (Details)	3 Months Ended			9 Months Ended
	Sep. 30, 2019 USD ($) Milestone shares	Sep. 30, 2018 USD ($) shares	Mar. 31, 2016 shares	Sep. 30, 2019 USD ($) Milestone tranche shares	Sep. 30, 2018 USD ($) shares	Mar. 31, 2019 shares	Dec. 31, 2018 USD ($) shares
Share-Based Compensation
Number of tranches \| tranche				3
Number of performance milestones \| Milestone	3			2
Share-based compensation expense	$ 13,019,000	$ 11,746,000		$ 36,538,000	$ 39,599,000
Research and development
Share-Based Compensation
Share-based compensation expense	6,458,000	6,294,000		18,338,000	19,757,000
Selling, general and administrative
Share-Based Compensation
Share-based compensation expense	$ 6,561,000	$ 5,452,000		$ 18,200,000	$ 19,842,000
Performance-Contingent Awards - RSAs
Share-Based Compensation
Shares approved for grant (in shares) \| shares			1,575,000
Vesting period			5 years
Awards outstanding (in shares) \| shares	776,250	978,750		776,250	978,750
Performance-Contingent Awards - RSUs
Share-Based Compensation
Shares approved for grant (in shares) \| shares	60,000		135,000	60,000		60,000
Awards outstanding (in shares) \| shares	101,250	101,250		101,250	101,250
Maximum potential expense \| Employee
Share-Based Compensation
Shares approved for grant (in shares) \| shares							3,000
Maximum potential expense \| Performance-Contingent Awards - RSUs
Share-Based Compensation
Share-based compensation expense	$ 1,000,000.0			$ 1,600,000
Maximum potential expense \| RSUs \| Employee \| Maximum
Share-Based Compensation
Compensation expense							$ 75,000
First tranche
Share-Based Compensation
Share-based compensation expense	300,000				$ 1,800,000
Second tranche
Share-Based Compensation
Share-based compensation expense	$ 700,000	$ 47,000		1,200,000	$ 1,800,000
Second tranche \| Maximum potential expense
Share-Based Compensation
Share-based compensation expense				1,100,000
Second tranche \| Maximum potential expense \| Research and development
Share-Based Compensation
Share-based compensation expense				400,000
Second tranche \| Maximum potential expense \| Selling, general and administrative
Share-Based Compensation
Share-based compensation expense				700,000
Third tranche
Share-Based Compensation
Share-based compensation expense				0
Third tranche \| Maximum potential expense
Share-Based Compensation
Share-based compensation expense				12,800,000
Third tranche \| Maximum potential expense \| Research and development
Share-Based Compensation
Share-based compensation expense				4,400,000
Third tranche \| Maximum potential expense \| Selling, general and administrative
Share-Based Compensation
Share-based compensation expense				$ 8,400,000
First and second performance milestones \| Performance-Contingent Awards - RSUs
Share-Based Compensation
Shares approved for grant (in shares) \| shares	60,000			60,000
First and second performance milestones \| Maximum potential expense \| Performance-Contingent Awards - RSUs
Share-Based Compensation
Share-based compensation expense				$ 800,000
Second and third performance milestones \| Performance-Contingent Awards - RSUs
Share-Based Compensation
Shares approved for grant (in shares) \| shares	60,000			60,000
Second and third performance milestones \| Maximum potential expense \| Performance-Contingent Awards - RSUs
Share-Based Compensation
Share-based compensation expense	$ 300,000