Segment Information - Percentage of Revenue (Details) - Total revenue - Customer concentration risk	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Janssen
Segment Information
Percentage of total revenues	51.00%
Alfasigma
Segment Information
Percentage of total revenues	18.00%
Cardinal Health
Segment Information
Percentage of total revenues	0.00%	28.00%
AmerisourceBergen Drug Corp
Segment Information
Percentage of total revenues	0.00%	25.00%
McKesson Corp
Segment Information
Percentage of total revenues	0.00%	23.00%
Besse Medical
Segment Information
Percentage of total revenues	0.00%	13.00%
Mylan
Segment Information
Percentage of total revenues	0.00%		31.00%
Takeda
Segment Information
Percentage of total revenues	0.00%		31.00%