The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACER THERAPEUTICS INC COM 00444P108 3,370 109,270 SH   SOLE   109,270 0 0
ALIMERA SCIENCES INC COM 016259103 262 267,500 SH   SOLE   267,500 0 0
AMAG PHARMACEUTICALS INC COM 00163U106 800 40,000 SH Put SOLE   40,000 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 1,155 71,000 SH   SOLE   71,000 0 0
ARGENX SE SPONSORED ADR 04016X101 7,963 105,000 SH   SOLE   105,000 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 14,857 775,000 SH   SOLE   775,000 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 3,834 200,000 SH Call SOLE   0 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 5,066 71,500 SH   SOLE   71,500 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 34,540 930,000 SH   SOLE   930,000 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 5,478 147,500 SH Call SOLE   0 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 4,975 132,500 SH   SOLE   132,500 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 2,020 53,800 SH Call SOLE   0 0 0
CAS MED SYS INC COM PAR 124769209 12,001 5,263,508 SH   SOLE   5,263,508 0 0
CHEMBIO DIAGNOSTICS INC COM NEW 163572209 21,321 2,030,533 SH   SOLE   2,030,533 0 0
COHERUS BIOSCIENCES INC COM 19249H103 5,833 353,500 SH   SOLE   353,500 0 0
COHERUS BIOSCIENCES INC COM 19249H103 825 50,000 SH Call SOLE   0 0 0
ENDOCYTE INC COM 29269A102 1,634 92,000 SH   SOLE   92,000 0 0
GTX INC DEL COM NEW 40052B207 157 100,000 SH Put SOLE   100,000 0 0
IMMUNOMEDICS INC COM 452907108 42,816 2,055,500 SH   SOLE   2,055,500 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 25,005 2,222,701 SH   SOLE   2,222,701 0 0
IRIDEX CORP COM 462684101 12,367 1,947,500 SH   SOLE   1,947,500 0 0
KADMON HLDGS INC COM 48283N106 24,699 7,395,000 SH   SOLE   7,395,000 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 2,849 128,844 SH   SOLE   128,844 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 7,066 33,000 SH   SOLE   33,000 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 2,042 170,000 SH   SOLE   170,000 0 0
ONCOBIOLOGICS INC COM 68235M105 29 29,082 SH   SOLE   29,082 0 0
REGENERON PHARMACEUTICALS COM 75886F107 8,081 20,000 SH Put SOLE   20,000 0 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 9,587 100,000 SH Put SOLE   100,000 0 0
VERACYTE INC COM 92337F107 10,433 1,092,500 SH   SOLE   1,092,500 0 0
VIEWRAY INC COM 92672L107 2,916 311,500 SH   SOLE   311,500 0 0
XENON PHARMACEUTICALS INC COM 98420N105 6,369 482,500 SH   SOLE   482,500 0 0