The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108 6,998 220,000 SH   SOLE   220,000 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 1,272 40,000 SH Call SOLE   0 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 10,567 280,000 SH   SOLE   280,000 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 2,249 59,600 SH Call SOLE   0 0 0
AGENUS INC COM NEW 00847G705 748 104,178 SH   SOLE   104,178 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 1,321 25,000 SH   SOLE   25,000 0 0
AKARI THERAPEUTICS PLC SPONSORED ADR 00972G108 197 23,169 SH   SOLE   23,169 0 0
AKEBIA THERAPEUTICS INC COM 00972D105 6,335 700,000 SH   SOLE   700,000 0 0
ALERE INC COM 01449J105 1,946 45,000 SH   SOLE   45,000 0 0
ALIMERA SCIENCES INC COM 016259103 1,452 974,318 SH   SOLE   974,318 0 0
AMICUS THERAPEUTICS INC COM 03152W109 4,958 670,000 SH   SOLE   670,000 0 0
APPLIED GENETIC TECHNOL CORP COM 03820J100 100 10,193 SH   SOLE   10,193 0 0
ARDELYX INC COM 039697107 337 26,076 SH   SOLE   26,076 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 7,296 363,000 SH   SOLE   363,000 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 2,265 314,211 SH   SOLE   314,211 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 986 30,000 SH   SOLE   30,000 0 0
ATRICURE INC COM 04963C209 1,047 66,186 SH   SOLE   66,186 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103 2,445 554,448 SH   SOLE   554,448 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103 473 107,200 SH Call SOLE   0 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103 223 50,600 SH Put SOLE   50,600 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 2,776 30,000 SH   SOLE   30,000 0 0
CAS MED SYS INC COM PAR $0.004 124769209 6,647 3,845,365 SH   SOLE   3,845,365 0 0
CEMPRA INC COM 15130J109 5,082 210,000 SH   SOLE   210,000 0 0
CHEMBIO DIAGNOSTICS INC COM NEW 163572209 5,710 771,676 SH   SOLE   771,676 0 0
COMBIMATRIX CORPORATION COM PAR 20009T501 133 47,431 SH   SOLE   47,431 0 0
CORBUS PHARMACEUTICALS HLDGS COM 21833P103 552 81,302 SH   SOLE   81,302 0 0
DBV TECHNOLOGIES S A SPONSORED ADR 23306J101 2,044 56,260 SH   SOLE   56,260 0 0
DERMIRA INC COM 24983L104 3,619 107,000 SH   SOLE   107,000 0 0
DEXTERA SURGICAL INC COM 252366109 242 128,958 SH   SOLE   128,958 0 0
EDGE THERAPEUTICS INC COM 279870109 7,318 703,000 SH   SOLE   703,000 0 0
EHI CAR SVCS LTD SPON ADS CL A 26853A100 603 58,827 SH   SOLE   58,827 0 0
ESSA PHARMA INC COM 29668H104 1,678 586,700 SH   SOLE   586,700 0 0
EVERYDAY HEALTH INC COM 300415106 11,920 1,550,000 SH   SOLE   1,550,000 0 0
GENOMIC HEALTH INC COM 37244C101 2,085 72,100 SH   SOLE   72,100 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 5,507 41,487 SH   SOLE   41,487 0 0
IMMUNOMEDICS INC NOTE 4.750% 2/1 452907AK4 6,333 7,500,000 PRN   SOLE   0 0 7,500,000
IMMUNOMEDICS INC COM 452907108 190 58,600 SH Call SOLE   0 0 0
IMMUNOMEDICS INC COM 452907108 12,513 3,850,000 SH   SOLE   3,850,000 0 0
INNOCOLL HLDGS PLC SHS G4783X105 3,902 671,517 SH   SOLE   671,517 0 0
IRIDEX CORP COM 462684101 17,687 1,220,611 SH   SOLE   1,220,611 0 0
ISHARES TR RUSSELL 2000 ETF 464287655 4,968 40,000 SH Put SOLE   40,000 0 0
LION BIOTECHNOLOGIES INC COM 53619R102 26,582 3,229,916 SH   SOLE   3,229,916 0 0
MANNKIND CORP COM 56400P201 56 90,000 SH Put SOLE   90,000 0 0
MARVELL TECHNOLOGY GROUP LTD ORD G5876H105 6,768 510,000 SH   SOLE   510,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 826 125,000 SH   SOLE   125,000 0 0
NABRIVA THERAPEUTICS AG SPONSORED ADR 62957M104 4,114 583,521 SH   SOLE   583,521 0 0
NEURODERM LTD ORD SHS M74231107 8,560 462,956 SH   SOLE   462,956 0 0
ONCOBIOLOGICS INC COM 68235M105 1,043 245,391 SH   SOLE   245,391 0 0
ONCOBIOLOGICS INC *W EXP 02/18/201 68235M113 47 96,833 SH   SOLE   96,833 0 0
ONCOBIOLOGICS INC *W EXP 05/18/201 68235M121 97 96,833 SH   SOLE   96,833 0 0
OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103 5,122 407,815 SH   SOLE   407,815 0 0
PERNIX THERAPEUTICS HLDGS IN COM 71426V108 46 73,500 SH Put SOLE   73,500 0 0
PROGENICS PHARMACEUTICALS IN COM 743187106 2,737 432,370 SH   SOLE   432,370 0 0
PROGENICS PHARMACEUTICALS IN COM 743187106 253 40,000 SH Call SOLE   0 0 0
RADIUS HEALTH INC COM NEW 750469207 2,164 40,000 SH   SOLE   40,000 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 367 100,000 SH Call SOLE   0 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 44 11,900 SH Put SOLE   11,900 0 0
SAREPTA THERAPEUTICS INC COM 803607100 3,071 50,000 SH   SOLE   50,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100 2,438 39,700 SH Call SOLE   0 0 0
SINOVAC BIOTECH LTD SHS P8696W104 1,206 204,358 SH   SOLE   204,358 0 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 9,944 150,000 SH Put SOLE   150,000 0 0
TENET HEALTHCARE CORP COM NEW 88033G407 743 32,809 SH   SOLE   32,809 0 0
TESARO INC COM 881569107 2,275 22,700 SH   SOLE   22,700 0 0
TROVAGENE INC COM NEW 897238309 359 80,000 SH Put SOLE   80,000 0 0
VANDA PHARMACEUTICALS INC COM 921659108 4,093 245,995 SH   SOLE   245,995 0 0
VERACYTE INC COM 92337F107 23,931 3,144,649 SH   SOLE   3,144,649 0 0
WEBMD HEALTH CORP COM 94770V102 4,722 95,000 SH   SOLE   95,000 0 0