AEGERION PHARMACEUTICALS INC NOTE 2.000% 8/1 00767EAB8 664 1000000 PRN SOLE 0 0 1000000 AKARI THERAPEUTICS PLC SPONSORED ADR 00972G108 247 17023 SH SOLE 17023 0 0 ALIMERA SCIENCES INC COM 016259103 2358 974318 SH SOLE 974318 0 0 AMICUS THERAPEUTICS INC COM 03152W109 14576 1502661 SH SOLE 1502661 0 0 ASCENDIS PHARMA A S SPONSORED ADR 04351P101 9513 519243 SH SOLE 519243 0 0 ATARA BIOTHERAPEUTICS INC COM 046513107 2509 95000 SH SOLE 95000 0 0 BIOTELEMETRY INC COM 090672106 1756 150322 SH SOLE 150322 0 0 BUILD A BEAR WORKSHOP COM 120076104 2045 167109 SH SOLE 167109 0 0 CARDICA INC COM 14141R101 183 1185029 SH SOLE 1185029 0 0 CARDIOME PHARMA CORP COM NO PAR 14159U301 669 82552 SH SOLE 82552 0 0 CAS MED SYS INC COM PAR $0.004 124769209 4517 2551803 SH SOLE 2551803 0 0 CEDAR FAIR L P DEPOSITRY UNIT 150185106 1202 21529 SH SOLE 21529 0 0 CEMPRA INC COM 15130J109 7783 250000 SH SOLE 250000 0 0 CLOVIS ONCOLOGY INC COM 189464100 1050 30000 SH Put SOLE 30000 0 0 COMBIMATRIX CORPORATION COM NEW 20009T303 520 711470 SH SOLE 711470 0 0 CUTERA INC COM 232109108 1456 113807 SH SOLE 113807 0 0 CYNAPSUS THERAPEUTICS INC COM PAR NO PAR 23257Y859 5759 376647 SH SOLE 376647 0 0 EDGE THERAPEUTICS INC COM 279870109 1985 158807 SH SOLE 158807 0 0 ESSA PHARMA INC COM 29668H104 1479 322500 SH SOLE 322500 0 0 EVERYDAY HEALTH INC COM 300415106 2157 358347 SH SOLE 358347 0 0 EXELIXIS INC COM 30161Q104 6812 1207726 SH SOLE 1207726 0 0 FLEX PHARMA INC COM 33938A105 1105 88716 SH SOLE 88716 0 0 HEARTWARE INTL INC COM 422368100 1743 34587 SH SOLE 34587 0 0 IMMUNOMEDICS INC COM 452907108 12170 3964033 SH SOLE 3964033 0 0 INCYTE CORP COM 45337C102 4780 44078 SH SOLE 44078 0 0 INNOCOLL AG SPONSORED ADR 45780Q103 2661 320555 SH SOLE 320555 0 0 IRIDEX CORP COM 462684101 4246 457000 SH SOLE 457000 0 0 KINDRED BIOSCIENCES INC COM 494577109 170 50000 SH SOLE 50000 0 0 LA JOLLA PHARMACEUTICAL CO COM PAR $.0001 2 503459604 2239 82920 SH SOLE 82920 0 0 LION BIOTECHNOLOGIES INC COM 53619R102 14784 1915000 SH SOLE 1915000 0 0 MIRATI THERAPEUTICS INC COM 60468T105 2795 88439 SH SOLE 88439 0 0 NABRIVA THERAPEUTICS AG SPONSORED ADR 62957M104 3971 412747 SH SOLE 412747 0 0 NEUROCRINE BIOSCIENCES INC COM 64125C109 3168 56000 SH SOLE 56000 0 0 NEURODERM LTD ORD SHS M74231107 8138 477300 SH SOLE 477300 0 0 OHR PHARMACEUTICAL INC COM NEW 67778H200 61 10000 SH Put SOLE 10000 0 0 ORTHOFIX INTL N V COM N6748L102 973 24813 SH SOLE 24813 0 0 OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103 2186 190100 SH SOLE 190100 0 0 PERNIX THERAPEUTICS HLDGS COM 71426V108 1281 434300 SH SOLE 434300 0 0 POWERSHARES QQQ TRUST UNIT SER 1 73935A104 5593 50000 SH Put SOLE 50000 0 0 QLT INC COM 746927102 801 301160 SH SOLE 301160 0 0 RETROPHIN INC COM 761299106 7137 370000 SH SOLE 370000 0 0 RIGEL PHARMACEUTICALS INC COM NEW 766559603 1382 456061 SH SOLE 456061 0 0 RR MEDIA LTD SHS M8183P102 4495 497227 SH SOLE 497227 0 0 SAGE THERAPEUTICS INC COM 78667J108 984 16877 SH SOLE 16877 0 0 SAGENT PHARMACEUTICALS INC COM 786692103 2302 144667 SH SOLE 144667 0 0 SAREPTA THERAPEUTICS INC COM 803607100 2894 75000 SH Call SOLE 0 0 0 SPDR SERIES TRUST S&P BIOTECH 78464A870 5616 80000 SH Put SOLE 80000 0 0 STRONGBRIDGE BIOPHARMA PLC SHS USD G85347105 6865 978907 SH SOLE 978907 0 0 TENET HEALTHCARE CORP COM NEW 88033G407 861 28400 SH SOLE 28400 0 0 UNIVERSAL DISPLAY CORP COM 91347P105 15646 287397 SH SOLE 287397 0 0 UNIVERSAL DISPLAY CORP COM 91347P105 6163 113200 SH Call SOLE 0 0 0 VANDA PHARMACEUTICALS INC COM 921659108 260 27952 SH SOLE 27952 0 0 VERACYTE INC COM 92337F107 12355 1716000 SH SOLE 1716000 0 0