ADVERUM BIOTECHNOLOGIES INC COM 00773U108 38 15000 SH SOLE 15000 0 0 ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 2828 20068 SH SOLE 20068 0 0 COSTAR GROUP INC COM 22160N109 47889 181672 SH SOLE 181672 0 0 CURRENCYSHARES EURO TR PUT 23130C958 997 9023 SH Put DFND 9023 0 0 CURRENCYSHS JAPANESE YEN TR JAPANESE YEN 23130A102 2672 31245 SH DFND 31245 0 0 EDITAS MEDICINE INC COM 28106W103 693 41324 SH DFND 41324 0 0 ISHARES TR JP MOR EM MK ETF 464288281 7943 70000 SH DFND 70000 0 0 KITE PHARMA INC COM 49803L109 249848 2410034 SH SOLE 2410034 0 0 LPL FINL HLDGS INC COM 50212V100 8801 208401 SH SOLE 208401 0 0 MIMEDX GROUP INC CALL 602496901 5853 391000 SH Call SOLE 391000 0 0 NANTHEALTH INC COM 630104107 531 125623 SH SOLE 125623 0 0 NANTHEALTH INC COM 630104107 479 113205 SH DFND 113205 0 0 NANTKWEST INC COM 63016Q102 25742 3391539 SH SOLE 3391539 0 0 PLAYA HOTELS & RESORTS NV SHS N70544106 3585 300000 SH SOLE 300000 0 0 POWERSHS DB MULTI SECT COMM CALL 73936D907 728 29400 SH Call DFND 29400 0 0 SABINE ROYALTY TR UNIT BEN INT 785688102 2859 74505 SH SOLE 74505 0 0 SORRENTO THERAPEUTICS INC COM NEW 83587F202 5352 2676193 SH SOLE 2676193 0 0 SORRENTO THERAPEUTICS INC COM NEW 83587F202 247 123597 SH DFND 123597 0 0 UNITI GROUP INC COM 91325V108 6612 263000 SH SOLE 263000 0 0 UROGEN PHARMA LTD COM M96088105 181 10000 SH SOLE 10000 0 0 UROGEN PHARMA LTD COM M96088105 2258 125000 SH DFND 125000 0 0