Consolidated Statements of Shareholders' Equity (Unaudited) - USD ($) $ in Thousands		Total		Convertible Preferred Shares [Member]	Common Shares [Member]	Additional Paid-in Capital [Member]	Accumulated Deficit [Member]	Accumulated Other Comprehensive Loss [Member]	[1]
Balance at Dec. 31, 2020		$ 171,355		$ 7,732	$ 397,748	$ 45,357	$ (278,492)	$ (990)
Balance (in Shares) at Dec. 31, 2020				1,016,000	35,012,125
Net loss		(15,764)					(15,764)
Issuance of common shares and pre-funded warrants, net of issuance costs (note 7a and note 7c)		118,615			$ 99,846	18,769
Issuance of common shares and pre-funded warrants, net of issuance costs (note 7a and note 7c) (in shares)					5,868,135
Stock-based compensation expense		1,965				1,965
Issued pursuant to exercise of stock options		106			$ 740	(634)
Issued pursuant to exercise of of stock options (in Shares)					82,455
Balance at Mar. 31, 2021		276,277		$ 7,732	$ 498,334	65,457	(294,256)	(990)
Balance (in Shares) at Mar. 31, 2021				1,016,000	40,962,715
Balance at Dec. 31, 2020		171,355		$ 7,732	$ 397,748	45,357	(278,492)	(990)
Balance (in Shares) at Dec. 31, 2020				1,016,000	35,012,125
Net loss		$ (37,873)
Issued pursuant to exercise of of stock options (in Shares)	[2]	344,734
Balance at Jun. 30, 2021		$ 256,983		$ 7,732	$ 499,351	67,255	(316,365)	(990)
Balance (in Shares) at Jun. 30, 2021				1,016,000	41,117,568
Balance at Mar. 31, 2021		276,277		$ 7,732	$ 498,334	65,457	(294,256)	(990)
Balance (in Shares) at Mar. 31, 2021				1,016,000	40,962,715
Net loss		(22,109)					(22,109)
Stock-based compensation expense		2,704				2,704
Issued pursuant to exercise of stock options		$ 111			$ 1,017	(906)
Issued pursuant to exercise of of stock options (in Shares)		222,331	[2]		154,853
Balance at Jun. 30, 2021		$ 256,983		$ 7,732	$ 499,351	67,255	(316,365)	(990)
Balance (in Shares) at Jun. 30, 2021				1,016,000	41,117,568
Balance at Dec. 31, 2021		550,033		$ 7,732	$ 783,170	117,495	(357,374)	(990)
Balance (in Shares) at Dec. 31, 2021				1,016,000	51,634,752
Net loss		(19,670)					(19,670)
Issuance of common shares and pre-funded warrants, net of issuance costs (note 7a and note 7c)		7,876			$ 7,876
Issuance of common shares and pre-funded warrants, net of issuance costs (note 7a and note 7c) (in shares)					258,986
Conversion of preferred shares to common shares (note 7b)				$ (7,732)	$ 7,732
Conversion of preferred shares to common shares (note 7b) (in shares)				(1,016,000)	1,016,000
Stock-based compensation expense		3,614				3,614
Issued pursuant to exercise of stock options					$ 1,529	(1,529)
Issued pursuant to exercise of of stock options (in Shares)					149,311
Balance at Mar. 31, 2022		541,853			$ 800,307	119,580	(377,044)	(990)
Balance (in Shares) at Mar. 31, 2022					53,059,049
Balance at Dec. 31, 2021		550,033		$ 7,732	$ 783,170	117,495	(357,374)	(990)
Balance (in Shares) at Dec. 31, 2021				1,016,000	51,634,752
Net loss		$ (50,828)
Issued pursuant to exercise of of stock options (in Shares)	[2]	349,138
Balance at Jun. 30, 2022		$ 785,793		$ 0	$ 1,061,690	133,295	(408,202)	(990)
Balance (in Shares) at Jun. 30, 2022				0	62,242,883
Balance at Mar. 31, 2022		541,853			$ 800,307	119,580	(377,044)	(990)
Balance (in Shares) at Mar. 31, 2022					53,059,049
Net loss		(31,158)					(31,158)
Issuance of common shares and pre-funded warrants, net of issuance costs (note 7a and note 7c)		269,890			$ 260,503	9,387
Issuance of common shares and pre-funded warrants, net of issuance costs (note 7a and note 7c) (in shares)					9,098,362
Stock-based compensation expense		$ 5,208				5,208
Issued pursuant to exercise of stock options					$ 880	(880)
Issued pursuant to exercise of of stock options (in Shares)		130,031	[2]		85,472
Balance at Jun. 30, 2022		$ 785,793		$ 0	$ 1,061,690	$ 133,295	$ (408,202)	$ (990)
Balance (in Shares) at Jun. 30, 2022				0	62,242,883

[1] The accumulated other comprehensive loss is entirely related to historical cumulative translation adjustments from the application of U.S. dollar reporting when the functional currency of the Company was the Canadian dollar.

[2] During the six months ended June 30, 2022, no stock options were exercised for cash (six months ended June 30, 2021 – 58,179)  . In the same period, the Company issued 234,783 (six months ended June 30, 2021 – 179,129) common shares for the cashless exercise of 349,138  (six months ended June 30, 2021 – 286,555) stock options.