Consolidated Statement of Shareholders' Equity - USD ($) $ in Thousands	Total		Convertible Preferred Shares [Member]	Common Shares [Member]	Additional Paid-in Capital [Member]	Accumulated Deficit [Member]	Accumulated Other Comprehensive Loss [Member]	[1]
Balance at Dec. 31, 2019	$ 91,977		$ 7,732	$ 294,244	$ 40,646	$ (249,655)	$ (990)
Balance (in Shares) at Dec. 31, 2019			1,016,000	28,139,228
Net loss	(28,837)					(28,837)
Issuance of common shares, net of issuance costs (note 10a)	102,456			$ 102,456
Issuance of common shares, net of issuance costs (note 10a) (in shares)				6,759,187
Stock-based compensation expense	5,677				5,677
Issued pursuant to exercise of stock options	$ 82			$ 1,048	(966)
Issued pursuant to exercise of stock options (in Shares)	171,812	[2]		113,710
Balance at Dec. 31, 2020	$ 171,355		$ 7,732	$ 397,748	45,357	(278,492)	(990)
Balance (in Shares) at Dec. 31, 2020			1,016,000	35,012,125
Net loss	(78,882)					(78,882)
Issuance of common shares, net of issuance costs (note 10a)	447,283			$ 381,567	65,716
Issuance of common shares, net of issuance costs (note 10a) (in shares)				16,143,472
Stock-based compensation expense	10,017				10,017
Issued pursuant to exercise of stock options	$ 260			$ 3,855	(3,595)
Issued pursuant to exercise of stock options (in Shares)	690,284	[2]		479,155
Balance at Dec. 31, 2021	$ 550,033		$ 7,732	$ 783,170	$ 117,495	$ (357,374)	$ (990)
Balance (in Shares) at Dec. 31, 2021			1,016,000	51,634,752

[1] The accumulated other comprehensive loss is entirely related to historical cumulative translation adjustments from the application of U.S. dollar reporting when the functional currency of the Company was the Canadian dollar.

[2] During the year ended December 31, 2021, 66,215 (2020 – 26,513) stock options were exercised for the same number of common shares in exchange for cash. In the same period, the Company issued 412,940 (2020 – 87,197) common shares for the cashless exercise of 624,069 (2020 – 145,299) stock options.