Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Income Statement [Abstract]
Revenue (note 12)	$ 18,437	$ 32,166
Operating expenses:
Research and development	75,463	50,523
General and administrative	21,967	12,944
Total operating expenses	97,430	63,467
Loss from operations	(78,993)	(31,301)
Other income (expense):
Interest income	466	2,279
Unrealized fair value gain (loss) on marketable securities	(719)	4
Interest expense		(484)
Foreign exchange gain	358	1,396
Loss on repayment of term loan (note 9)		(988)
Loss before income taxes	(78,888)	(29,094)
Income tax recovery (note 14)	6	257
Net loss and comprehensive loss	(78,882)	(28,837)
Net loss attributable to preferred shareholders	(1,795)	(824)
Net loss attributable to common shareholders	$ (77,087)	$ (28,013)
Net loss per common share (note 5):
Basic and diluted	$ (1.77)	$ (0.81)
Weighted-average common shares outstanding (note 5):
Basic and diluted	43,627,452	34,542,213