Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Current assets:
Cash and cash equivalents	$ 175,688	$ 45,009
Marketable securities	376,086	131,988
Accounts receivable	2,765	1,822
Prepaid expenses and other current assets	4,481	2,964
Total current assets	559,020	181,783
Operating lease right-of-use asset, net (note 7)	8,056	3,326
Property, plant and equipment, net (note 6)	4,466	3,554
Deferred tax assets (note 14)	465	523
Total assets	572,007	189,186
Current liabilities:
Accounts payable and accrued expenses (note 8)	13,717	10,874
Deferred revenue (note 12)		3,642
Operating lease liability (note 7)	605	265
Total current liabilities	14,322	14,781
Operating lease liability, long-term (note 7)	7,652	3,050
Total liabilities	21,974	17,831
Shareholders’ equity:
Preferred shares, without par value; unlimited shares authorized; issued and outstanding: 1,016,000 (December 31, 2020 - 1,016,000) (note 10)	7,732	7,732
Common shares, without par value; unlimited shares authorized; issued and outstanding: 51,634,752 (December 31, 2020 - 35,012,125) (note 10)	783,170	397,748
Additional paid-in capital	117,495	45,357
Accumulated deficit	(357,374)	(278,492)
Accumulated other comprehensive loss	(990)	(990)
Shareholders' equity	550,033	171,355
Total liabilities and shareholders’ equity	572,007	189,186
Commitments and contingencies (note 13)