Share Capital (Details) - USD ($) $ / shares in Units, $ in Thousands	1 Months Ended							3 Months Ended			9 Months Ended	12 Months Ended
	Sep. 30, 2021	Mar. 31, 2021	Aug. 31, 2020	Feb. 29, 2020	Jan. 31, 2020	Nov. 30, 2019	Mar. 31, 2018	Sep. 30, 2021	Mar. 31, 2021	Mar. 31, 2020	Sep. 30, 2021	Dec. 31, 2019	Dec. 31, 2018
Share Capital [Line Items]
Amount offered for issuance of common stock								$ 4,730		$ 102,456
Warrants outstanding to purchase common stock	1,081,081							1,081,081			1,081,081
Warrants exercise description		The Company may not affect the exercise of any Pre-Funded Warrant, and a holder will not be entitled to exercise any portion of any Pre-Funded Warrant that, upon giving effect to such exercise, would cause: (i) the aggregate number of common shares beneficially owned by such holder, together with its affiliates, to exceed 4.99% of the total number of common shares outstanding immediately after giving effect to the exercise; or (ii) the combined voting power of the Company’s securities beneficially owned by such holder, together with its affiliates, to exceed 4.99% of the combined voting power of all of the Company’s securities immediately outstanding after giving effect to the exercise, which percentage may be changed at the holder’s election to a higher or lower percentage not in excess of 19.99% upon at least 61 days’ notice to the Company.
Series1 Preferred Shares
Share Capital [Line Items]
Conversion of shares													1,852,000
Common Shares [Member]
Share Capital [Line Items]
Conversion of shares													1,852,000
BVF Partners L.P [Member] | Exchange Agreement [Member]
Share Capital [Line Items]
Estimated weighted average cancellation price per share of common stock							$ 7.61
BVF Partners L.P [Member] | Exchange Agreement [Member] | Series1 Preferred Shares
Share Capital [Line Items]
Shares issued							2,868,000
Preferred shares convertible into common shares							one-for-one
Maximum beneficial ownership limitation percentage for conversion of common stock issued and outstanding							9.99%
Maximum beneficial ownership limitation upon notice, percentage for conversion of common stock issued and outstanding							19.99%
Maximum beneficial percentage hold for conversion of number Of common stock issued and outstanding							5.00%
Minimum beneficial percentage hold for conversion of number Of common stock issued and outstanding.							5.00%
BVF Partners L.P [Member] | Exchange Agreement [Member] | Common Shares [Member]
Share Capital [Line Items]
Shares cancelled							2,868,000
Common Shares [Member]
Share Capital [Line Items]
Shares issued								275,337	5,868,135	6,759,187
Amount offered for issuance of common stock								$ 4,730	$ 99,846	$ 102,456
Common Shares [Member] | Neurocrine Collaboration Agreement [Member]
Share Capital [Line Items]
Amount offered for issuance of common stock	$ 5,500
Shares issued	275,337
Aggregate purchase price per share	$ 19.9755							$ 19.9755			$ 19.9755
Common stock purchase price premium at fair value	$ 770
Lock-up restrictions and standstill agreement period	2 years
Jefferies and Stifel [Member] | Underwritten Public Offering [Member]
Share Capital [Line Items]
Amount offered for issuance of common stock		$ 107,922
Shares issued		5,135,135
Shares price		$ 18.50							$ 18.50
Warrants outstanding to purchase common stock		1,081,081							1,081,081
Warrants issued price per pre funded warrant		$ 18.4999							$ 18.4999
Warrants exercise price per common share		$ 0.0001							$ 0.0001
Sale proceeds from issuance of pre funded warrants		$ 18,769
Number of warrants exercised											0
Jefferies and Stifel [Member] | At-The-Market Equity Offering [Member]
Share Capital [Line Items]
Amount offered for issuance of common stock					$ 37,796							$ 10,729
Sale proceeds of common shares											10,693,000
Jefferies and Stifel [Member] | At-The-Market Equity Offering [Member] | Maximum [Member]
Share Capital [Line Items]
Amount offered for issuance of common stock						$ 50,000
Amount offered for issuance of common stock			$ 100,000
Jefferies and Stifel [Member] | At-The-Market Equity Offering [Member] | Common Shares [Member]
Share Capital [Line Items]
Shares issued					2,446,687						733,000	805,643
Jefferies and Stifel [Member] | Over Allotment [Member]
Share Capital [Line Items]
Shares issued		810,810
Jefferies, Stifel and Guggenheim Securities, LLC [Member] | Underwritten Public Offering [Member]
Share Capital [Line Items]
Amount offered for issuance of common stock				$ 8,395	$ 56,265
Jefferies, Stifel and Guggenheim Securities, LLC [Member] | Underwritten Public Offering [Member] | Common Shares [Member]
Share Capital [Line Items]
Shares issued				562,500	3,750,000
Shares price					$ 16.00