Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2020	Dec. 31, 2019
Current assets:
Cash and cash equivalents	$ 45,009	$ 24,755
Marketable securities	131,988	116,603
Accounts receivable	1,822	813
Prepaid expenses and other current assets	2,964	2,695
Total current assets	181,783	144,866
Operating lease right-of-use asset, net (note 8)	3,326	933
Property, plant and equipment, net (note 7)	3,554	1,660
Deferred tax assets (note 15)	523	238
Total assets	189,186	147,697
Current liabilities:
Accounts payable and accrued expenses (note 9)	10,874	8,818
Deferred revenue (note 13)	3,642	29,743
Operating lease liability (note 8)	265	168
Term loan (note 10)		4,650
Total current liabilities	14,781	43,379
Deferred revenue, long-term (note 13)		709
Operating lease liability, long-term (note 8)	3,050	743
Term loan, long-term (note 10)		10,889
Total liabilities	17,831	55,720
Shareholders’ equity:
Preferred shares, without par value; unlimited shares authorized; issued and outstanding: 1,016,000 (December 31, 2019 - 1,016,000) (note 11)	7,732	7,732
Common shares, without par value; unlimited shares authorized; issued and outstanding: 35,012,125 (December 31, 2019 - 28,139,228) (note 11)	397,748	294,244
Additional paid-in capital	45,357	40,646
Accumulated deficit	(278,492)	(249,655)
Accumulated other comprehensive loss	(990)	(990)
Shareholders' equity	171,355	91,977
Total liabilities and shareholders’ equity	189,186	147,697
Commitments and contingencies (note 14)