Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2019	Dec. 31, 2018
Current assets:
Cash and cash equivalents	$ 24,755	$ 67,754
Marketable securities	116,603	51,552
Accounts receivable	813	151
Prepaid expenses and other current assets	2,695	1,875
Total current assets	144,866	121,332
Operating lease right-of-use asset (note 8)	933
Property, plant and equipment, net (note 7)	1,660	991
Deferred tax assets (note 15)	238	105
Total assets	147,697	122,428
Current liabilities:
Accounts payable and accrued expenses (note 9)	8,818	4,119
Deferred revenue (note 13)	29,743
Operating lease liability (note 8)	168
Term loan (note 10)	4,650
Total current liabilities	43,379	4,119
Deferred revenue, long-term (note 13)	709
Operating lease liability, long-term (note 8)	743
Term loan, long-term (note 10)	10,889	15,014
Total liabilities	55,720	19,133
Shareholders’ equity:
Preferred shares, without par value; unlimited shares authorized; issued and outstanding: 1,016,000 (December 31, 2018 - 1,016,000) (note 11)	7,732	7,732
Common shares, without par value; unlimited shares authorized; issued and outstanding: 28,139,228 (December 31, 2018 - 25,750,721) (note 11)	294,244	265,923
Additional paid-in capital	40,646	38,515
Accumulated deficit	(249,655)	(207,885)
Accumulated other comprehensive loss	(990)	(990)
Shareholders' equity	91,977	103,295
Total liabilities and shareholders’ equity	147,697	122,428
Commitments and contingencies (note 14)