Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Current assets:
Cash and cash equivalents	$ 67,754	$ 20,486
Marketable securities	51,552	23,181
Accounts receivable	256	438
Prepaid expenses and other current assets	1,875	716
Total current assets	121,437	44,821
Prepaid expenses, long-term		230
Property, plant and equipment, net (note 7)	991	1,070
Total assets	122,428	46,121
Current liabilities:
Accounts payable and accrued expenses (note 8)	4,119	3,383
Loan payable, current portion (note 9)		700
Total current liabilities	4,119	4,083
Loan payable, long-term (note 9)	15,014	6,104
Total liabilities	19,133	10,187
Shareholders’ equity:
Preferred shares, without par value; unlimited shares authorized; issued and outstanding: 1,016,000 (December 31, 2017 - nil) (note 10)	7,732
Common shares, without par value; unlimited shares authorized; issued and outstanding: 25,750,721 (December 31, 2017 - 17,998,420) (note 10)	265,923	173,841
Additional paid-in capital	38,515	36,471
Accumulated deficit	(207,885)	(173,388)
Accumulated other comprehensive loss	(990)	(990)
Shareholders' equity	103,295	35,934
Total liabilities and shareholders’ equity	122,428	46,121
Commitments and contingencies (note 13)