Selected Quarterly Consolidated Financial Data (Unaudited)

12 Months Ended

Dec. 31, 2017

Quarterly Financial Information Disclosure [Abstract]

Selected Quarterly Consolidated Financial Data (Unaudited)

15. Selected quarterly consolidated financial data (unaudited):

The following table presents certain unaudited quarterly consolidated financial information for the years ended December 31, 2017 and 2016 (in thousands of U.S. dollars except per share amounts). This information reflects all normal recurring adjustments, which are, in the opinion of management, necessary for a fair statement of the results of the interim periods.

	Three Months Ended
	March 31, 2017			June 30, 2017			September 30, 2017			December 31, 2017
Revenue	$	16		$	15		$	264		$	16
Loss from operations		(7,987	)		(7,893	)		(8,644	)		(8,051	)
Net loss		(7,517	)		(7,380	)		(7,742	)		(8,065	)
Basic net loss per common share	$	(0.42	)	$	(0.41	)	$	(0.43	)	$	(0.45	)
Diluted net loss per common share	$	(0.43	)	$	(0.41	)	$	(0.43	)	$	(0.45	)
	Three Months Ended
	March 31, 2016			June 30, 2016			September 30, 2016			December 31, 2016
Revenue	$	601		$	413		$	413		$	376
Loss from operations		(5,658	)		(6,366	)		(7,331	)		(5,462	)
Net loss		(3,263	)		(6,016	)		(7,714	)		(6,004	)
Basic and diluted net loss per common share	$	(0.23	)	$	(0.42	)	$	(0.51	)	$	(0.34	)