Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2017	Jun. 30, 2016	Jun. 30, 2017	Jun. 30, 2016
Revenue:
Collaboration revenue (note 8)	$ 15	$ 412	$ 30	$ 981
Royalties		1	1	33
Revenues	15	413	31	1,014
Operating expenses:
Research and development	6,109	5,103	12,012	9,467
General and administrative	1,799	1,676	3,899	3,571
Total operating expenses	7,908	6,779	15,911	13,038
Loss from operations	(7,893)	(6,366)	(15,880)	(12,024)
Other income:
Interest income	109	123	258	222
Foreign exchange gain	404	227	725	2,523
Net loss and comprehensive loss	$ (7,380)	$ (6,016)	$ (14,897)	$ (9,279)
Net loss per common share (note 4):
Basic	$ (0.41)	$ (0.42)	$ (0.83)	$ (0.64)
Diluted	$ (0.41)	$ (0.42)	$ (0.84)	$ (0.65)
Weighted-average common shares outstanding (note 4):
Basic	17,997,194	14,408,108	17,971,702	14,401,054
Diluted	18,015,748	14,434,602	17,995,109	14,428,160