Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2017	Mar. 31, 2016
Revenue:
Collaboration revenue (note 8)	$ 15	$ 569
Royalties	1	32
Revenues	16	601
Operating expenses:
Research and development	5,903	4,364
General and administrative	2,100	1,895
Total operating expenses	8,003	6,259
Loss from operations	(7,987)	(5,658)
Other income:
Interest income	149	99
Foreign exchange gain	321	2,296
Net loss and comprehensive loss	$ (7,517)	$ (3,263)
Net loss per common share (note 4):
Basic	$ (0.42)	$ (0.23)
Diluted	$ (0.43)	$ (0.23)
Weighted-average common shares outstanding (note 4):
Basic	17,946,209	14,394,000
Diluted	17,974,469	14,394,000