Statements of Operations and Comprehensive Income (Loss) (Unaudited) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Revenue:
Collaboration revenue (note 8)	$ 412	$ 4,044	$ 981	$ 8,054
Royalties	1	2	33	2
Revenues	413	4,046	1,014	8,056
Operating expenses:
Research and development	5,103	3,669	9,467	7,096
General and administrative	1,676	178	3,571	6,898
Total operating expenses	6,779	3,847	13,038	13,994
Income (loss) from operations	(6,366)	199	(12,024)	(5,938)
Other income (expense):
Interest income	123	163	222	315
Foreign exchange gain (loss)	227	806	2,523	(2,365)
Net income (loss) and comprehensive income (loss)	$ (6,016)	$ 1,168	$ (9,279)	$ (7,988)
Net income (loss) per common share (note 4):
Basic	$ (0.42)	$ 0.08	$ (0.64)	$ (0.56)
Diluted	$ (0.42)	$ (0.07)	$ (0.65)	$ (0.56)
Weighted-average common shares outstanding (note 4):
Basic	14,408,108	14,241,827	14,401,054	14,227,203
Diluted	14,434,602	15,129,978	14,428,160	14,227,203