Collaboration Agreements (Tables)

12 Months Ended

Dec. 31, 2015

Organization Consolidation And Presentation Of Financial Statements [Abstract]

Schedule of Revenues from Collaborations

The following table is a summary of the revenue recognized from the Company’s collaborations for each of the years ended December 31, 2015, 2014 and 2013.

	Year Ended December 31,
	2015		2014		2013
uniQure:
Milestone payment	$	—	$	14	$	531
Teva:
Recognition of upfront payment		10,897		12,255		13,143
Research funding		112		333		630
Genentech:
Recognition of upfront payment		725		3,603		3,300
Research funding		3,589		4,248		4,514
Milestone payment		250		7,913		5,062
Genome BC:
Research funding		—		—		172
Total collaboration revenue	$	15,573	$	28,366	$	27,352