Statements of Cash Flows - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2015	Sep. 30, 2014
Operating activities:
Net income (loss)	$ (11,815)	$ 11,794
Adjustments to reconcile net income (loss) to net cash used in operating activities:
Depreciation and amortization	754	533
Stock-based compensation	3,255	561
Deferred tenant inducements	(47)	(50)
Unrealized foreign exchange loss	5,486	52
Changes in operating assets and liabilities:
Accounts receivable	(61)	267
Prepaid expenses, and other current assets	315	(27)
Prepaid expenses, long term	(1,700)
Accounts payable and accrued expenses	223	614
Deferred revenue	(9,266)	(10,527)
Net cash provided by (used in) operating activities	(12,856)	3,217
Investing activities:
Purchases of property, plant and equipment	(408)	(753)
Purchase of marketable securities		(15,334)
Proceeds from marketable securities	10,745	11,803
Net cash provided by (used in) investing activities	10,337	(4,284)
Financing activities:
Deferred financing fees		(1,305)
Proceeds from issuance of common shares	240	10
Net cash provided by (used in) financing activities	240	(1,295)
Effect of exchange rate changes on cash and cash equivalents	(4,278)	(1,857)
Decrease in cash and cash equivalents	(6,557)	(4,219)
Cash and cash equivalents, beginning of period	72,026	37,950
Cash and cash equivalents, end of period	65,469	33,731
Supplemental disclosures:
Interest received	550	439
Supplemental disclosures of non-cash transactions:
Issuance of common shares on conversion of subscription rights		$ 32
Fair value of options exercised on a cashless basis	$ 544