16.	Related parties:

Genworks Inc. (“Genworks”) is controlled by a director of the Company who is the president and principal beneficial shareholder of Genworks. Genworks provided certain scientific consulting services to the Company pursuant to a consulting agreement. The Company did not incur any cash consulting fees to Genworks for the year ended December 31, 2014 (2013 - nil, 2012 - $307).

On January 1, 2012, the Company granted Genworks an option to purchase 10,288 of its common shares at an exercise price of CAD$3.74 per share and on January 1, 2013, the Company granted Genworks an option to purchase 30,864 of its common shares at an exercise price of CAD$2.67 per share. Pursuant to a performance bonus awarded to Genworks in acknowledgment of services conducted prior to September 1, 2012 relating to the Company’s sublicense agreement with uniQure, in the event that the Company receives royalty payments from uniQure satisfying certain pre-specified thresholds, Genworks has a right to receive a portion of such royalty payments, totaling up to CAD$600. As of September 1, 2012, no further fees or bonuses are payable to Genworks under such consulting agreement.

No amounts have been accrued as of December 31, 2014 (December 31, 2013 - nil) relating to services provided by Genworks.

One of the Company’s directors is a former equity holder and former director of Medpace, Inc. (“Medpace”). The Company did not incur any contract research organization fees to Medpace for the year ended December 31, 2014 (2013 - nil, 2012 - $151). Previously incurred contract research organization fees were paid to Medpace in consideration of certain clinical development services provided by Medpace by individuals other than the Company’s director. None of these fees were paid directly to the Company’s director. No amounts have been accrued as of December 31, 2014 (December 31, 2013 - nil) relating to services provided by Medpace.