Consolidated Statements of Shareholders' Equity - USD ($) $ in Thousands	Total	Common Shares [Member]	Additional Paid-in Capital [Member]	Accumulated Deficit [Member]	Accumulated Other Comprehensive Loss [Member]
Balance at Dec. 31, 2022	$ 721,497	$ 1,065,136	$ 142,108	$ (482,747)	$ (3,000)
Balance (in Shares) at Dec. 31, 2022		62,587,701
Net loss for the year	(182,393)			(182,393)
Issuance of common shares and pre-funded warrants, net	353,487	$ 330,010	23,477
Issuance of common shares and pre-funded warrants, net (in shares)		10,701,842
Conversion of pre-funded warrants		$ 35,913	(35,913)
Conversion of pre-funded warrants (in shares)		1,700,000
Stock-based compensation expense	32,372		32,372
Issuance of common shares pursuant to equity incentive plans	35	$ 5,315	(5,280)
Issuance of common shares pursuant to equity incentive plans (in shares)		381,434
Other comprehensive income (loss)	2,923				2,923
Balance at Dec. 31, 2023	927,921	$ 1,436,374	156,764	(665,140)	(77)
Balance (in Shares) at Dec. 31, 2023		75,370,977
Net loss for the year	(234,330)			(234,330)
Issuance of common shares and pre-funded warrants, net	12,083	$ 12,083
Issuance of common shares and pre-funded warrants, net (in shares)		310,000
Stock-based compensation expense	50,717		50,717
Issuance of common shares pursuant to equity incentive plans	47	$ 8,379	(8,332)
Issuance of common shares pursuant to equity incentive plans (in shares)		735,109
Other comprehensive income (loss)	(1,535)				(1,535)
Balance at Dec. 31, 2024	754,903	$ 1,456,836	199,149	(899,470)	(1,612)
Balance (in Shares) at Dec. 31, 2024		76,416,086
Net loss for the year	(345,910)			(345,910)
Issuance of common shares and pre-funded warrants, net	112,151	$ 112,151
Issuance of common shares and pre-funded warrants, net (in shares)		2,651,023
Conversion of warrant		$ 291	(291)
Conversion of warrant (in shares)		30,792
Stock-based compensation expense	53,707		53,707
Issuance of common shares pursuant to equity incentive plans	4,962	$ 29,293	(24,331)
Issuance of common shares pursuant to equity incentive plans (in shares)		912,889
Other comprehensive income (loss)	1,947				1,947
Balance at Dec. 31, 2025	$ 581,760	$ 1,598,571	$ 228,234	$ (1,245,380)	$ 335
Balance (in Shares) at Dec. 31, 2025		80,010,790