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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Operating activities:    
Net loss $ (149,753) $ (105,855)
Adjustments to reconcile net loss to net cash used in operating activities:    
Interest receivable and accretion of discounts on marketable securities 6,505 (1,482)
Depreciation of property plant and equipment 1,291 1,227
Non-cash operating lease expense 649 620
Deferred income tax expense (recovery) (1,383) 70
Stock-based compensation 25,887 24,116
Unrealized foreign exchange (gain) loss (28) 118
Realized loss on marketable securities 518 0
Changes in operating assets and liabilities:    
Other receivables 380 16
Prepaid expenses and other current assets (6,412) 285
Accounts payable and accrued liabilities (2,914) 4,135
Operating lease liability (625) (589)
Net cash used in operating activities (125,885) (77,339)
Investing activities:    
Purchases of property, plant and equipment (200) (1,702)
Purchases of marketable securities (220,055) (301,826)
Proceeds from marketable securities 337,025 369,527
Net cash provided by investing activities 116,770 65,999
Financing activities:    
Proceeds from exercise of stock options 1,216 0
Net cash provided by financing activities 1,216 0
Effect of exchange rate changes on cash and cash equivalents 568 (569)
Decrease in cash and cash equivalents (7,331) (11,909)
Cash and cash equivalents, beginning of period 142,712 148,643
Cash and cash equivalents, end of period 135,381 136,734
Supplemental disclosure of cash paid:    
Operating lease 845 819
Income taxes 7,897  
Supplemental disclosures of non-cash transactions:    
Fair value of stock options exercised on a cashless basis $ 10,324 $ 4,084