Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024
Income Statement [Abstract]
Collaboration revenue (note 9)	$ 7,500	$ 0
Operating expenses:
Research and development	61,200	44,250
General and administrative	19,038	14,791
Total operating expenses	80,238	59,041
Loss from operations	(72,738)	(59,041)
Other income:
Interest income	8,083	11,355
Foreign exchange gain (loss)	35	167
Other income	8,118	11,522
Loss before income taxes	(64,620)	(47,519)
Income tax expense	(427)	(412)
Net loss	(65,047)	(47,931)
Other comprehensive income (loss):
Unrealized gain (loss) on available-for-sale securities (note 5)	776	(1,692)
Comprehensive loss	$ (64,271)	$ (49,623)
Net loss per common share (note 10):
Basic	$ (0.83)	$ (0.62)
Diluted	$ (0.83)	$ (0.62)
Weighted-average common shares outstanding (note 10):
Basic	78,687,503	77,594,599
Diluted	78,687,503	77,594,599