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Segment Disclosure (Tables)
3 Months Ended
Mar. 31, 2025
Segment Reporting [Abstract]  
Summary of Net Loss Related To Segment Expenses

The following table presents information about reported segment revenues, significant segment expenses, and segment loss:

 

 

 

Three Months Ended March 31,

 

 

 

2025

 

 

2024

 

Collaboration revenue

 

$

7,500

 

 

$

 

 

 

 

 

 

 

 

Less:

 

 

 

 

 

 

Direct external research and development costs

 

 

 

 

 

 

Azetukalner

 

 

31,501

 

 

 

23,213

 

Pre-clinical, discovery and other programs

 

 

4,967

 

 

 

3,661

 

Personnel-related expenses

 

 

22,640

 

 

 

14,854

 

Stock-based compensation expense

 

 

12,174

 

 

 

9,400

 

Other research and development costs

 

 

3,425

 

 

 

3,014

 

Other general and administrative costs

 

 

5,531

 

 

 

4,899

 

Interest income

 

 

(8,083

)

 

 

(11,355

)

Other segment items(1)

 

 

392

 

 

 

245

 

Net loss

 

$

(65,047

)

 

$

(47,931

)

(1)
Other segment items include foreign exchange gain and income tax expense.