Condensed Consolidated Balance Sheets (Unaudited) - USD ($) $ in Thousands	Mar. 31, 2025	Dec. 31, 2024
Current assets:
Cash and cash equivalents	$ 116,657	$ 142,712
Marketable securities (note 5)	432,972	484,193
Accounts and other receivable	8,649	1,469
Prepaid expenses and other current assets	7,259	6,890
Total current assets	565,537	635,264
Marketable securities, long-term (note 5)	141,498	127,496
Operating lease right-of-use asset, net (note 6)	7,617	7,939
Property, plant and equipment, net	9,696	10,278
Deferred tax assets	10,879	9,666
Prepaid expenses, long-term	8,053	7,496
Total assets	743,280	798,139
Current liabilities:
Accounts payable and accrued liabilities (note 7)	30,648	34,221
Operating lease liability (note 6)	1,382	1,369
Total current liabilities	32,030	35,590
Operating lease liability, long-term (note 6)	7,293	7,646
Total liabilities	39,323	43,236
Shareholders’ equity:
Common shares, without par value; unlimited shares authorized; issued and outstanding: 76,586,359 (December 31, 2024 - 76,416,086) (note 8)	1,460,850	1,456,836
Additional paid-in capital	208,460	199,149
Accumulated deficit	(964,517)	(899,470)
Accumulated other comprehensive loss	(836)	(1,612)
Total shareholders' equity	703,957	754,903
Total liabilities and shareholders’ equity	743,280	798,139
Commitments and contingencies (note 11)