Consolidated Statements of Shareholders' Equity - USD ($) $ in Thousands	Total	Convertible Preferred Shares [Member]	Common Shares [Member]	Additional Paid-in Capital [Member]	Accumulated Deficit [Member]	Accumulated Other Comprehensive Loss [Member]
Balance at Dec. 31, 2021	$ 550,033	$ 7,732	$ 783,170	$ 117,495	$ (357,374)	$ (990)
Balance (in Shares) at Dec. 31, 2021		1,016,000	51,634,752
Net loss for the year	(125,373)				(125,373)
Issuance of common shares and pre-funded warrants, net (note 9a and note 9e)	277,766		$ 268,379	9,387
Issuance of common shares and pre-funded warrants, net (note 9a and note 9e) (in shares)			9,357,348
Conversion of preferred shares (note 9d)		$ (7,732)	$ 7,732
Conversion of preferred shares (note 9d) (in shares)		(1,016,000)	1,016,000
Stock-based compensation expense (note 9c)	20,376			20,376
Exercise of stock options	$ 705		$ 5,855	(5,150)
Exercise of stock options (in Shares)	780,725		579,601
Other comprehensive (loss) income	$ (2,010)					(2,010)
Balance at Dec. 31, 2022	721,497		$ 1,065,136	142,108	(482,747)	(3,000)
Balance (in Shares) at Dec. 31, 2022			62,587,701
Net loss for the year	(182,393)				(182,393)
Issuance of common shares and pre-funded warrants, net (note 9a and note 9e)	353,487		$ 330,010	23,477
Issuance of common shares and pre-funded warrants, net (note 9a and note 9e) (in shares)			10,701,842
Conversion of pre-funded warrants (note 9e)			$ 35,913	(35,913)
Conversion of pre-funded warrants (note 9e) (in shares)			1,700,000
Stock-based compensation expense (note 9c)	32,372			32,372
Exercise of stock options	$ 35		$ 5,315	(5,280)
Exercise of stock options (in Shares)	587,536		381,434
Other comprehensive (loss) income	$ 2,923					2,923
Balance at Dec. 31, 2023	927,921		$ 1,436,374	156,764	(665,140)	(77)
Balance (in Shares) at Dec. 31, 2023			75,370,977
Net loss for the year	(234,330)				(234,330)
Issuance of common shares and pre-funded warrants, net (note 9a and note 9e)	12,083		$ 12,083
Issuance of common shares and pre-funded warrants, net (note 9a and note 9e) (in shares)			310,000
Stock-based compensation expense (note 9c)	50,717			50,717
Exercise of stock options	$ 47		$ 8,379	(8,332)
Exercise of stock options (in Shares)	1,040,136		735,109
Other comprehensive (loss) income	$ (1,535)					(1,535)
Balance at Dec. 31, 2024	$ 754,903		$ 1,456,836	$ 199,149	$ (899,470)	$ (1,612)
Balance (in Shares) at Dec. 31, 2024			76,416,086