Consolidated Balance Sheets (Unaudited) - USD ($) $ in Thousands	Sep. 30, 2023	Dec. 31, 2022
Current assets:
Cash and cash equivalents	$ 99,574	$ 57,242
Marketable securities (note 5)	427,100	534,845
Accounts receivable	805	986
Prepaid expenses and other current assets	3,529	7,225
Total current assets	531,008	600,298
Marketable securities, long-term (note 5)	112,407	128,682
Operating lease right-of-use asset, net (note 6)	9,497	10,406
Property, plant and equipment, net	10,236	6,500
Deferred tax assets	601	509
Prepaid expenses, long-term	7,344	7,751
Total assets	671,093	754,146
Current liabilities:
Accounts payable and accrued expenses (note 7)	23,498	22,214
Operating lease liability (note 6)	1,246	488
Total current liabilities	24,744	22,702
Operating lease liability, long-term (note 6)	9,757	9,947
Total liabilities	34,501	32,649
Shareholders’ equity:
Common shares, without par value; unlimited shares authorized; issued and outstanding: 65,002,249 (December 31, 2022 - 62,587,701) (note 8)	1,121,968	1,065,136
Additional paid-in capital	137,974	142,108
Accumulated deficit	(620,397)	(482,747)
Accumulated other comprehensive loss	(2,953)	(3,000)
Total shareholders' equity	636,592	721,497
Total liabilities and shareholders’ equity	671,093	754,146
Commitments and contingencies (note 10)