Consolidated Balance Sheets (Unaudited) - USD ($) $ in Thousands	Jun. 30, 2023	Dec. 31, 2022
Current assets:
Cash and cash equivalents	$ 64,552	$ 57,242
Marketable securities (note 5)	475,048	534,845
Accounts receivable	2,123	986
Prepaid expenses and other current assets	2,893	7,225
Total current assets	544,616	600,298
Marketable securities, long-term (note 5)	112,592	128,682
Operating lease right-of-use asset, net (note 6)	9,799	10,406
Property, plant and equipment, net	9,563	6,500
Deferred tax assets	445	509
Prepaid expenses, long-term	7,884	7,751
Total assets	684,899	754,146
Current liabilities:
Accounts payable and accrued expenses (note 7)	26,936	22,214
Operating lease liability (note 6)	1,223	488
Total current liabilities	28,159	22,702
Operating lease liability, long-term (note 6)	10,283	9,947
Total liabilities	38,442	32,649
Shareholders’ equity:
Common shares, without par value; unlimited shares authorized; issued and outstanding: 63,718,350 (December 31, 2022 - 62,587,701) (note 8)	1,083,008	1,065,136
Additional paid-in capital	138,683	142,108
Accumulated deficit	(571,935)	(482,747)
Accumulated other comprehensive loss	(3,299)	(3,000)
Total shareholders' equity	646,457	721,497
Total liabilities and shareholders’ equity	684,899	754,146
Commitments and contingencies (note 10)