Consolidated Statements of Shareholders' Equity (Unaudited) - USD ($) $ in Thousands	Total	Convertible Preferred Shares [Member]	Common Shares [Member]	Additional Paid-in Capital [Member]	Accumulated Deficit [Member]	Accumulated Other Comprehensive Loss [Member]
Balance at Dec. 31, 2020	$ 171,355	$ 7,732	$ 397,748	$ 45,357	$ (278,492)	$ (990)
Balance (in Shares) at Dec. 31, 2020		1,016,000	35,012,125
Net loss	(15,764)				(15,764)
Issuance of common shares and pre-funded warrants, net of issuance costs (note 9a and note 9c)	118,615		$ 99,846	18,769
Issuance of common shares and pre-funded warrants, net of issuance costs (note 9a and note 9c) (in shares)			5,868,135
Stock-based compensation expense	1,965			1,965
Issued pursuant to exercise of stock options	106		$ 740	(634)
Issued pursuant to exercise of stock options (in Shares)			82,455
Balance at Mar. 31, 2021	276,277	$ 7,732	$ 498,334	65,457	(294,256)	(990)
Balance (in Shares) at Mar. 31, 2021		1,016,000	40,962,715
Balance at Dec. 31, 2020	171,355	$ 7,732	$ 397,748	45,357	(278,492)	(990)
Balance (in Shares) at Dec. 31, 2020		1,016,000	35,012,125
Net loss	$ (53,318)
Issued pursuant to exercise of stock options (in Shares)	386,708
Balance at Sep. 30, 2021	$ 248,939	$ 7,732	$ 504,386	69,621	(331,810)	(990)
Balance (in Shares) at Sep. 30, 2021		1,016,000	41,412,875
Balance at Mar. 31, 2021	276,277	$ 7,732	$ 498,334	65,457	(294,256)	(990)
Balance (in Shares) at Mar. 31, 2021		1,016,000	40,962,715
Net loss	(22,109)				(22,109)
Stock-based compensation expense	2,704			2,704
Issued pursuant to exercise of stock options	111		$ 1,017	(906)
Issued pursuant to exercise of stock options (in Shares)			154,853
Balance at Jun. 30, 2021	256,983	$ 7,732	$ 499,351	67,255	(316,365)	(990)
Balance (in Shares) at Jun. 30, 2021		1,016,000	41,117,568
Net loss	(15,445)				(15,445)
Issuance of common shares and pre-funded warrants, net of issuance costs (note 9a and note 9c)	4,730		$ 4,730
Issuance of common shares and pre-funded warrants, net of issuance costs (note 9a and note 9c) (in shares)			275,337
Stock-based compensation expense	2,643			2,643
Issued pursuant to exercise of stock options	$ 28		$ 305	(277)
Issued pursuant to exercise of stock options (in Shares)	41,974		19,970
Balance at Sep. 30, 2021	$ 248,939	$ 7,732	$ 504,386	69,621	(331,810)	(990)
Balance (in Shares) at Sep. 30, 2021		1,016,000	41,412,875
Balance at Dec. 31, 2021	550,033	$ 7,732	$ 783,170	117,495	(357,374)	(990)
Balance (in Shares) at Dec. 31, 2021		1,016,000	51,634,752
Net loss	(19,670)				(19,670)
Issuance of common shares and pre-funded warrants, net of issuance costs (note 9a and note 9c)	7,876		$ 7,876
Issuance of common shares and pre-funded warrants, net of issuance costs (note 9a and note 9c) (in shares)			258,986
Conversion of preferred shares to common shares (note 9b)		$ (7,732)	$ 7,732
Conversion of preferred shares to common shares (note 9b) (in shares)		(1,016,000)	1,016,000
Stock-based compensation expense	3,614			3,614
Issued pursuant to exercise of stock options			$ 1,529	(1,529)
Issued pursuant to exercise of stock options (in Shares)			149,311
Balance at Mar. 31, 2022	541,853		$ 800,307	119,580	(377,044)	(990)
Balance (in Shares) at Mar. 31, 2022			53,059,049
Balance at Dec. 31, 2021	550,033	$ 7,732	$ 783,170	117,495	(357,374)	(990)
Balance (in Shares) at Dec. 31, 2021		1,016,000	51,634,752
Net loss	$ (87,978)
Issued pursuant to exercise of stock options (in Shares)	718,472
Balance at Sep. 30, 2022	$ 753,119		$ 1,064,698	136,728	(445,352)	(2,955)
Balance (in Shares) at Sep. 30, 2022			62,542,542
Balance at Mar. 31, 2022	541,853		$ 800,307	119,580	(377,044)	(990)
Balance (in Shares) at Mar. 31, 2022			53,059,049
Net loss	(31,158)				(31,158)
Issuance of common shares and pre-funded warrants, net of issuance costs (note 9a and note 9c)	269,890		$ 260,503	9,387
Issuance of common shares and pre-funded warrants, net of issuance costs (note 9a and note 9c) (in shares)			9,098,362
Stock-based compensation expense	5,208			5,208
Issued pursuant to exercise of stock options			$ 880	(880)
Issued pursuant to exercise of stock options (in Shares)			85,472
Balance at Jun. 30, 2022	785,793	$ 0	$ 1,061,690	133,295	(408,202)	(990)
Balance (in Shares) at Jun. 30, 2022		0	62,242,883
Net loss	(37,150)				(37,150)
Stock-based compensation expense	5,742			5,742
Issued pursuant to exercise of stock options	$ 699		$ 3,008	(2,309)
Issued pursuant to exercise of stock options (in Shares)	369,334		299,659
Other comprehensive loss	$ (1,965)					(1,965)
Balance at Sep. 30, 2022	$ 753,119		$ 1,064,698	$ 136,728	$ (445,352)	$ (2,955)
Balance (in Shares) at Sep. 30, 2022			62,542,542