<?xml version="1.0"?>
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    <periodOfReport>2022-04-18</periodOfReport>

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        <issuerName>Cannabis Sativa, Inc.</issuerName>
        <issuerTradingSymbol>CBDS</issuerTradingSymbol>
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            <rptOwnerStreet2></rptOwnerStreet2>
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            <rptOwnerState>NV</rptOwnerState>
            <rptOwnerZipCode>89024</rptOwnerZipCode>
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            <officerTitle>CEO</officerTitle>
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                <sharesOwnedFollowingTransaction>
                    <value>3143905.0000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2022-05-16</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>5372.0000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.1370</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3138533.0000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">Conversion from Preferred to Common Stock</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ David Tobias</signatureName>
        <signatureDate>2024-02-27</signatureDate>
    </ownerSignature>
</ownershipDocument>
