Consolidated Statements of Cash Flows (unaudited) - USD ($) $ in Thousands	6 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Cash flows from operating activities
Net loss	$ (106,231)	$ (70,819)
Adjustments to reconcile net loss to net cash used in operating activities
Depreciation and amortization	7,118	4,575
Deferred tax liability	(11,045)	0
Loss on disposal of property and equipment	0	2
Non-cash lease expense	1,609	214
Stock-based compensation	40,573	18,575
Discount accretion on investment securities	790	314
Realized gain on investments	0	(4)
Non-cash interest expense	3	44
Bad debt expense	(180)	417
Amortization of debt discount	4	53
Contingent consideration and holdbacks	(8,840)	0
Write off property and equipment	70	0
Changes in assets and liabilities:
Accounts receivable, net	(3,845)	(1,331)
Inventories	(12,787)	(3,544)
Prepaid expenses and other current assets	(1,407)	(2,731)
Other non-current assets	3,873	(87)
Accounts payable	(762)	3,798
Accrued expenses	1,885	(45)
Accrued compensation	(653)	(38)
Other liabilities	832	1,126
Net cash used in operating activities	(88,993)	(49,481)
Cash flows from investing activities
Purchases of property and equipment	(44,753)	(12,030)
Business acquisition, net of cash acquired	(8,160)	0
Purchases of investments	(217,639)	(58,795)
Proceeds from maturity of investments	30,676	98,494
Net cash (used in) provided by investing activities	(239,876)	27,669
Cash flows from financing activities
Proceeds from exercise of stock options	4,000	9,116
Proceeds from public offerings, net of underwriting discounts, commissions and offering expenses	269,818	323,887
Proceeds from issuance of common stock under employee stock purchase plan	2,395	2,787
Repayments of long-term debt	(1,558)	(1,667)
Repurchases of common stock for income tax withholding	(4,050)	(5,751)
Net cash provided by financing activities	270,605	328,372
Effect of exchange rates on cash, cash equivalents and restricted cash	104	53
Net increase (decrease) in cash, cash equivalents, and restricted cash	(58,160)	306,613
Cash, cash equivalents, and restricted cash at beginning of period	467,359	94,246
Cash, cash equivalents, and restricted cash at end of period	409,199	400,859
Supplemental disclosure of cash flow information
Interest paid	9	109
Income taxes paid, net of refunds	130	1
Non-cash investing and financing activities
Property and equipment additions included in accounts payable and accrued expenses	8,737	197
Operating lease right-of-use assets obtained in exchange for operating lease liabilities	19,494	63
Issuance of common stock in connection with the business acquisition	$ 77,122	$ 0