X0306 4 2022-02-08 0 0001581280 Twist Bioscience Corp TWST 0001219039 CRANDELL KEITH 8755 W. HIGGINS ROAD, SUITE 1025 CHICAGO IL 60631 1 0 0 0 Common Stock 2022-02-08 4 A 0 3491 0.00 A 3977 D Common Stock 76047 I By Keith L. Crandell Trust 100% of the Shares subject to the Annual Equity Award will vest upon the earlier of (i) the one-year anniversary of the date of grant and (ii) the date of the first annual meeting of stockholders following the date of grant, provided that the Non-Employee Director is a Service Provider on each vesting date. /s/ William Solis, as Attorney-in-Fact for Keith Crandell 2022-02-10