X0306 4 2022-06-15 0 0001580063 BIORA THERAPEUTICS, INC. BIOR 0001892397 Howe Jill Ann C/O BIORA THERAPEUTICS, INC. 4330 LA JOLLA VILLAGE DRIVE, SUITE 300 SAN DIEGO CA 92122 1 0 0 0 Common Stock 2022-06-15 4 A 0 96154 0.00 A 172908 D Stock Option (Right to Buy) 0.64 2022-06-15 4 A 0 148810 0.00 A 2032-06-15 Common Stock 148810 148810 D Represents 96,154 restricted stock units, which vest in full on the earlier of (1) June 15, 2023 or (2) the date of the Issuer's 2023 annual meeting of stockholders, subject to the Reporting Person's continued service to the Issuer. This option represents the right to purchase 148,810 shares of the Issuer's common stock, which vest in full on the earlier of (1) June 15, 2023 or (2) the date of the Issuer's 2023 annual meeting of stockholders, subject to the Reporting Person's continued service to the Issuer. /s/ Will Pridgen, Attorney-in-Fact for Jill Howe 2022-06-17