X0306 4 2022-05-15 0 0001580063 BIORA THERAPEUTICS, INC. BIOR 0001321466 NEUMANN CLARKE C/O BIORA THERAPEUTICS, INC. 4330 LA JOLLA VILLAGE DRIVE, SUITE 300 SAN DIEGO CA 92122 0 1 0 0 See Remarks Common Stock 2022-05-15 4 F 0 8305 0.75 D 308320 D Common Stock 2022-05-15 4 A 0 239962 0.00 A 548282 D Stock Option (Right to Buy) 0.75 2022-05-15 4 A 0 387752 0.00 A 2032-05-15 Common Stock 387752 387752 D Represents shares withheld by the Issuer to satisfy tax withholding obligations in connection with the release of 24,014 vested restricted stock units on May 15, 2022. Consists of 239,962 restricted stock units, 25% of which will vest on May 15, 2023, with the remaining shares vesting in equal semi-annual installments through May 15, 2026, subject to the Reporting Person's continued service to the Issuer. This option represents the right to purchase 387,752 shares of the Issuer's common stock, 8,078 of which vested upon grant, with the remaining shares vesting in equal monthly installments through April 15, 2026, subject to the Reporting Person's continued service to the Issuer. Senior Vice President, General Counsel and Secretary /s/ Will Pridgen, Attorney-in-Fact for Clarke Neumann 2022-05-17