X0306 4 2022-05-15 0 0001580063 BIORA THERAPEUTICS, INC. BIOR 0001622268 dEsparbes Eric C/O BIORA THERAPEUTICS, INC. 4330 LA JOLLA VILLAGE DRIVE, SUITE 300 SAN DIEGO CA 92122 0 1 0 0 Chief Financial Officer Common Stock 2022-05-15 4 F 0 10387 0.75 D 412784 D Common Stock 2022-05-15 4 A 0 292406 0.00 A 705190 D Stock Option (Right to Buy) 0.75 2022-05-15 4 A 0 472495 0.00 A 2032-05-15 Common Stock 472495 472495 D Represents shares withheld by the Issuer to satisfy tax withholding obligations in connection with the release of 20,948 vested restricted stock units on May 15, 2022. Consists of 292,406 restricted stock units, 25% of which will vest on May 15, 2023, with the remaining shares vesting in equal semi-annual installments through May 15, 2026, subject to the Reporting Person's continued service to the Issuer. This option represents the right to purchase 472,495 shares of the Issuer's common stock, 9,843 of which vested upon grant, with the remaining shares vesting in equal monthly installments through April 15, 2026, subject to the Reporting Person's continued service to the Issuer. /s/ Will Pridgen, Attorney-in-Fact for Eric d'Esparbes 2022-05-17