Consolidated Statements of Stockholders' Equity - USD ($)	Total	License Agreement	Common Stock	Common Stock License Agreement	Additional Paid-in Capital	Additional Paid-in Capital License Agreement	Accumulated Deficit
Beginning balance at Dec. 31, 2017	$ 16,717,223		$ 2,549		$ 93,299,517		$ (76,584,843)
Balance (in shares) at Dec. 31, 2017			25,492,992
Stock-based compensation	1,754,974				1,754,974
Issuance of common stock upon exercise of options	380,322		$ 29		380,293
Issuance of common stock upon exercise of options (in shares)			278,925
Exercise of warrants	131,703		$ 10		131,693
Exercise of warrants (in shares)			101,310
Issuance of warrants upon debt financing	37,842				37,842
Issuance of common stock upon financing	12,881,321		$ 421		12,880,900
Issuance of common stock upon financing (in shares)			4,213,986
Net loss	(30,965,464)						(30,965,464)
Ending balance at Dec. 31, 2018	937,921		$ 3,009		108,485,219		(107,550,307)
Balance (in shares) at Dec. 31, 2018			30,087,213
Stock-based compensation	6,115,160				6,115,160
Issuance of common stock upon exercise of options	1,143,841		$ 25		1,143,816
Issuance of common stock upon exercise of options (in shares)			252,773
Exercise of warrants	249,836		$ 10		249,826
Exercise of warrants (in shares)			97,541
Issuance of warrants upon debt financing	387,000				387,000
Issuance of common stock upon financing	238,233,817		$ 649		238,233,168
Issuance of common stock upon financing (in shares)			6,495,690
Net loss	(68,345,186)						(68,345,186)
Ending balance at Dec. 31, 2019	$ 178,722,389		$ 3,693		354,614,189		(175,895,493)
Balance (in shares) at Dec. 31, 2019	36,933,217		36,933,217
Stock-based compensation	$ 14,756,206				14,756,206
Issuance of common stock upon exercise of options	$ 1,049,849		$ 13		1,049,836
Issuance of common stock upon exercise of options (in shares)	127,778		127,778
Exercise of warrants	$ 6		$ 6
Exercise of warrants (in shares)			63,831
Issuance of warrants upon debt financing	884,216				884,216
Issuance of common stock upon financing	14,125,506	$ 7,155,337	$ 17	$ 8	14,125,489	$ 7,155,329
Issuance of common stock upon financing (in shares)			167,243	82,019
Net loss	(102,900,600)						(102,900,600)
Ending balance at Dec. 31, 2020	$ 113,792,909		$ 3,737		$ 392,585,265		$ (278,796,093)
Balance (in shares) at Dec. 31, 2020	37,374,088		37,374,088