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Consolidated Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Cash flows from operating activities      
Net loss $ (68,345,186) $ (30,965,464) $ (28,943,392)
Adjustments to reconcile net loss to net cash used in operating activities:      
Stock-based compensation expense 6,115,160 1,754,974 2,072,210
Amortization of debt discount 649,993 375,635 470,521
Change in fair value of warrants   (2,791,000) 646,000
Depreciation 37,330 48,935 42,557
Changes in operating assets and liabilities:      
Prepaid expenses and other current assets 833,265 32,058 102,143
Other assets (27,530) 75,607 (75,131)
Accounts payable 7,256,080 251,789 (645,717)
Accrued expenses and other current liabilities 7,105,829 1,163,765 (140,843)
Net cash used in operating activities (46,375,059) (30,053,701) (26,471,652)
Cash flows from investing activities      
Purchases of equipment (16,121) (32,696) (9,898)
Net cash used in investing activities (16,121) (32,696) (9,898)
Cash flows from financing activities      
Payment of debt issuance costs   (25,997)  
Procceds from issuance of common stock upon financing, net 238,233,817 12,881,321 23,677,341
Proceeds from issuance of term loan 20,000,000    
Repayment of principal on term loan (7,238,889) (3,333,333) (277,778)
Proceeds from issuance of common stock upon exercise of options 1,143,841 380,322 316,719
Proceeds issuance of common stock upon exercise of warrants 249,836 131,703 167,894
Net cash (used in) provided by financing activities 252,388,605 10,034,016 23,884,176
Net (decrease) increase in cash 205,997,425 (20,052,381) (2,597,374)
Cash at beginning of period 13,968,742 34,021,123 36,618,497
Cash at end of period 219,966,167 13,968,742 34,021,123
Supplemental disclosures of cash flow information:      
Interest paid 1,287,506 771,966 865,278
Supplemental disclosures of non-cash financing activity:      
Establishment of warrant liabilities in connection with common stock issuance     $ 2,145,000
Issuance of warrants in connection with debt financing $ 387,000 $ 37,842