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Warrants - Background Information (Details) - USD ($)
12 Months Ended
Dec. 04, 2017
Nov. 03, 2014
Oct. 29, 2013
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Nov. 30, 2016
Nov. 09, 2016
Warrants                
Warrants outstanding beginning balance       337,696 272,468 230,409    
Warrants issued       1,890,602 65,228 42,059    
Warrants exercised       (129,149)        
Warrants outstanding ending balance       2,099,149 337,696 272,468    
Weighted average exercise price                
Beginning balance (in dollars per share)       $ 3.06 $ 2.02 $ 1.30    
Issued (in dollars per share)       5.33 7.41 5.94    
Exercised (in dollars per share)       1.30        
Ending balance (in dollars per share)       $ 5.21 $ 3.06 $ 2.02    
Value of warrants issued         $ 264,365      
Common warrants                
Warrants                
Warrants issued 1,783,587              
Weighted average exercise price                
Ending balance (in dollars per share) $ 5.25              
Placement agent warrants                
Warrants                
Warrants issued 107,015              
Weighted average exercise price                
Ending balance (in dollars per share) $ 6.6562              
Term Loan                
Weighted average exercise price                
Common stock to be issued if warrants are exercised (in shares)             65,228 65,228
June 2013 Notes                
Weighted average exercise price                
Exercised (in dollars per share)     $ 1.30          
Common stock to be issued if warrants are exercised (in shares)     230,409          
September 2014 Notes                
Weighted average exercise price                
Ending balance (in dollars per share)   $ 5.94            
Common stock to be issued if warrants are exercised (in shares)   42,059            
Fair value of warrant recorded as a debt discount   $ 79,129            
Mandatory conversion, warrant price premium as a percent of the conversion price   10.00%