Consolidated Statements of Stockholders' Equity (Deficit) - USD ($)	Common Stock	Additional paid-in capital	Accumulated deficit	Total
Beginning balance at Dec. 31, 2014	$ 1,111	$ 5,025,533	$ (8,229,219)	$ (3,202,575)
Balance (in shares) at Dec. 31, 2014	11,108,144
Stock-based compensation		803,279		803,279
Issuance of common stock in initial public offering, net of expense	$ 567	45,505,934		45,506,501
Issuance of common stock in initial public offering, net of expense (in shares)	5,666,667
Issuance of common stock for conversion of convertible notes	$ 237	15,302,624		15,302,861
Issuance of common stock for conversions of convertible notes (in shares)	2,374,606
Reclassification of warrant liability		244,774		244,774
Net loss			(12,210,579)	(12,210,579)
Ending balance at Dec. 31, 2015	$ 1,915	66,882,144	(20,439,798)	46,444,261
Balance (in shares) at Dec. 31, 2015	19,149,417
Stock-based compensation		2,031,418		2,031,418
Issuance of common stock in initial public offering, net of expense	$ 1	33,029		33,030
Issuance of common stock in initial public offering, net of expense (in shares)	9,000
Issuance of warrants		264,395		264,395
Net loss			(27,201,653)	(27,201,653)
Ending balance at Dec. 31, 2016	$ 1,916	69,210,986	(47,641,451)	$ 21,571,451
Balance (in shares) at Dec. 31, 2016	19,158,417			19,158,417
Stock-based compensation		2,072,210		$ 2,072,210
Proceeds from exercise of options	$ 9	316,710		$ 316,719
Proceeds from exercise of options (in shares)	88,922			88,922
Issuance of warrants	$ 13	167,881		$ 167,894
Issuance of warrants (in shares)	129,149
Issuance of stock upon financing	$ 611	21,531,730		21,532,341
Issuance of common stock upon financing (in shares)	6,116,504
Net loss			(28,943,392)	(28,943,392)
Ending balance at Dec. 31, 2017	$ 2,549	$ 93,299,517	$ (76,584,843)	$ 16,717,223
Balance (in shares) at Dec. 31, 2017	25,492,992			25,492,992