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Consolidated Statements of Operations - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Operating expenses:        
Research and development $ 5,568,777 $ 1,524,395 $ 15,393,089 $ 4,569,072
General and administrative 1,639,026 499,421 4,524,859 1,472,671
Total operating expenses 7,207,803 2,023,816 19,917,948 6,041,743
Loss from operations (7,207,803) (2,023,816) (19,917,948) (6,041,743)
Interest and other income (expense) 13,219 (279,802) 45,233 (619,645)
Change in fair value of warrant liability   (32,005)   (14,563)
Change in fair value of embedded derivative liabilities   204,000   274,800
Loss on extinguishment of debt   (2,444,516)   (2,444,516)
Net loss $ (7,194,584) $ (4,576,139) $ (19,872,715) $ (8,845,667)
Net loss per common share, basic and diluted $ (0.38) $ (0.41) $ (1.04) $ (0.80)
Weighted average common shares outstanding, basic and diluted 19,149,906 11,108,144 19,149,579 11,108,144