<SEC-DOCUMENT>0001047469-17-006481-index.html : 20171020
<SEC-HEADER>0001047469-17-006481.hdr.sgml : 20171020
<ACCEPTANCE-DATETIME>20171020170314
ACCESSION NUMBER:		0001047469-17-006481
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		3
FILED AS OF DATE:		20171020
DATE AS OF CHANGE:		20171020

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Axsome Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001579428
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				454241907
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-214859
		FILM NUMBER:		171147519

	BUSINESS ADDRESS:	
		STREET 1:		25 BROADWAY, 9TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10004
		BUSINESS PHONE:		212-203-5072

	MAIL ADDRESS:	
		STREET 1:		25 BROADWAY, 9TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10004
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B5
<SEQUENCE>1
<FILENAME>a2233589z424b5.htm
<DESCRIPTION>424B5
<TEXT>
Document 1 - file: a2233589z424b5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>g179565.jpg
<DESCRIPTION>G179565.JPG
<TEXT>
Document 2 - file: g179565.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>g753784.jpg
<DESCRIPTION>G753784.JPG
<TEXT>
Document 3 - file: g753784.jpg

</DOCUMENT>
</SEC-DOCUMENT>