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CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		15
FILED AS OF DATE:		20250807
DATE AS OF CHANGE:		20250807
EFFECTIVENESS DATE:		20250807

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Axsome Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001579428
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				454241907
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-289385
		FILM NUMBER:		251195022

	BUSINESS ADDRESS:	
		STREET 1:		ONE WORLD TRADE CENTER, 29TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10007
		BUSINESS PHONE:		(212) 332-3241

	MAIL ADDRESS:	
		STREET 1:		ONE WORLD TRADE CENTER, 29TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10007
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