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License Agreements - Additional Information (Details)
$ / shares in Units, € in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Jan. 31, 2020
USD ($)
$ / shares
shares
Mar. 31, 2025
USD ($)
Item
shares
Mar. 31, 2025
EUR (€)
Item
Mar. 31, 2024
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2012
Item
Dec. 31, 2024
USD ($)
shares
Jan. 09, 2020
USD ($)
$ / shares
Research And Development Arrangement Contract To Perform For Others [Line Items]                
Number of common shares | shares   49,216,759         48,667,587  
Value of common stock   $ 5,000         $ 5,000  
Research and development expense recognized   44,785,000   $ 36,830,000        
License Agreement | Antecip                
Research And Development Arrangement Contract To Perform For Others [Line Items]                
Milestone payments or royalties   2,900,000   1,600,000        
Accrued royalty payments   $ 2,900,000   $ 1,600,000        
Number of exclusive license agreements | Item   3 3     3    
License agreement royalty as a percent of net sales   3.00% 3.00% 3.00%        
License agreement royalty, maximum reduction percent as a result of required third party payments           50.00%    
License agreement term, from first commercial sale           10 years    
License Agreement | Antecip | AXS-05                
Research And Development Arrangement Contract To Perform For Others [Line Items]                
License agreement royalty as a percent of net sales           3.00%    
License Agreement | Antecip | Other Two Products | Minimum                
Research And Development Arrangement Contract To Perform For Others [Line Items]                
License agreement royalty as a percent of net sales           1.50%    
License Agreement | Antecip | Other Two Products | Maximum                
Research And Development Arrangement Contract To Perform For Others [Line Items]                
License agreement royalty as a percent of net sales           4.50%    
Pfizer Inc | License Agreement                
Research And Development Arrangement Contract To Perform For Others [Line Items]                
Number of common shares | shares 82,019              
Value of common stock $ 8,000,000              
Prior trading days 10 days              
Share price | $ / shares $ 97.54              
Upfront cash payment $ 3,000,000              
Fair value share price | $ / shares               $ 87.24
Fair value of common stock               $ 7,200,000
Research and development expense recognized         $ 10,200,000      
Future milestone payments   $ 323,000,000            
Milestone payments or royalties   0   $ 0        
Pharmanovia | License Agreement                
Research And Development Arrangement Contract To Perform For Others [Line Items]                
Non-refundable upfront payment received   65,700,000 € 62.0          
Eligible to receive sales-based and other milestones | €     € 94.5          
Royalty revenue   1,100,000   900,000        
Other development and sales based milestones recognized   $ 0   $ 0