<SEC-DOCUMENT>0000950170-23-018997-index.html : 20230509
<SEC-HEADER>0000950170-23-018997.hdr.sgml : 20230509
<ACCEPTANCE-DATETIME>20230508184131
ACCESSION NUMBER:		0000950170-23-018997
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		4
FILED AS OF DATE:		20230509
DATE AS OF CHANGE:		20230508
EFFECTIVENESS DATE:		20230509

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Axsome Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001579428
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				454241907
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-271741
		FILM NUMBER:		23899422

	BUSINESS ADDRESS:	
		STREET 1:		ONE WORLD TRADE CENTER, 22ND FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10007
		BUSINESS PHONE:		(212) 332-3241

	MAIL ADDRESS:	
		STREET 1:		ONE WORLD TRADE CENTER, 22ND FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10007
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
<SEQUENCE>1
<FILENAME>s-8_2023.htm
<DESCRIPTION>S-8
<TEXT>
Document 1 - file: s-8_2023.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5
<SEQUENCE>2
<FILENAME>axsm-ex5_1.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 2 - file: axsm-ex5_1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23
<SEQUENCE>3
<FILENAME>axsm-ex23_2.htm
<DESCRIPTION>EX-23.2
<TEXT>
Document 3 - file: axsm-ex23_2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>4
<FILENAME>axsm-exfiling_fees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 4 - file: axsm-exfiling_fees.htm

</DOCUMENT>
</SEC-DOCUMENT>